Real Betis came from behind to beat Real Madrid, with Isco scoring the winner against his former club.
The visitors, who sit second in La Liga, went ahead when Kylian Mbappé picked out Ferland Mendy, who squared for Brahim Díaz to slot into an empty net from close range.
Madrid had a couple of chances to double their lead before Johnny Cardoso equalized with a 34th-minute header from Isco’s corner.
Isco, captaining Betis against the club where he spent nine years, then netted a 54th-minute penalty after Antonio Rüdiger had fouled Jesús Rodríguez in the box.
It was the fourth time this season Carlo Ancelotti’s side has lost in La Liga, and they remain behind Barcelona on goal difference.
